drug design

Peptides

GLP-1 Under the Microscope: What Liraglutide's Self-Assembly Reveals About the Next Wave of Weight-Loss Drugs

A new flow-NMR study cracks open how a marketed GLP-1 drug quietly rearranges itself in solution — and why that matters for the next generation of injectables busy men will actually use.

Peptides

Why GLP-1 Drugs Last for Days: The Lipid Trick Behind Semaglutide's Half-Life

Native GLP-1 vanishes from your bloodstream in minutes. A fatty-acid tail turns it into a once-weekly shot — but the same trick that buys time also makes the drug harder to manufacture.