lysosomes

Longevity

The Sirtuin–Senescence Axis: Mapping the Molecular Drivers of Aging

Three converging 2025 reviews sketch an integrated picture of why tissues deteriorate—and where senolytics, NAD+ modulators, and lysosome-restoring therapies might one day intervene.

Longevity

The New Aging Hallmarks: Why Lysosomes, Senescent Cells, and Translation Errors Are the Next Frontier

Three 2025 papers are quietly reshaping the science of why we age — and where the next generation of interventions may aim. Here is what to know, and what to hold loosely.