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Three converging 2025 reviews sketch an integrated picture of why tissues deteriorate—and where senolytics, NAD+ modulators, and lysosome-restoring therapies might one day intervene.
A 2025 GeroScience paper finds that in aged mice under chronic stress, NR protected some blood markers — but also amplified anxiety-like behavior. A wrinkle worth knowing before your next scoop.
A single mechanism paper gives a long-suspected 'longevity vitamin' its first credible story — in worms and aged rats. Humans are not worms.