Longevity
The Senescence-Cancer Crossover: A Metabolic Brake on Aging Cells
New 2025 research reframes senescent and tumor cells as biological cousins — and points to putrescine as an unexpected checkpoint in how cells decide to age.
cellular aging
Longevity
The Nucleolus as Aging's Hidden Clock: New Mechanistic Targets for Geroprotection
A tiny structure inside every cell may act as a countdown timer for lifespan — and a new wave of AI-guided drug discovery and senescence-targeting therapies is racing to slow it down.
Longevity
The New Aging Hallmarks: Why Lysosomes, Senescent Cells, and Translation Errors Are the Next Frontier
Three 2025 papers are quietly reshaping the science of why we age — and where the next generation of interventions may aim. Here is what to know, and what to hold loosely.
Longevity
Rewriting the mTOR Aging Playbook: From YTHDF1 to Curcumin
Two new studies sharpen the picture of mTOR as an aging lever — pointing toward more precise ways to dial it down than blunt suppression.