osteoporosis

Longevity

Senolytics Go Mainstream: Killing Zombie Cells to Save Aging Bones

Two 2025 studies converge on a striking thesis — that clearing senescent cells, with drugs or even intermittent pressure, may halt age-related bone loss in mice. Here's what the preclinical signal actually says.

Protocols

Bone Health Before Spine Surgery: Which Anabolic Drugs Actually Move the Needle?

A single-institution analysis used CT-derived Hounsfield Units to compare modern osteoporosis drugs in preoperative patients. The signal is real but moderate — and frailty quietly blunts the response.