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A once-daily oral GLP-1, fresh data linking the class to lower lumbar disease risk, and a network meta-analysis hinting at a nuanced colorectal cancer question. Here's what the moderate evidence actually says.
New research in young adults links long-term obesity to measurable biological aging — and points to metabolism as the load-bearing pillar of longevity.
A new phase 3 trial shows a once-daily pill can deliver meaningful weight loss without a needle — and that small detail could change who actually gets treated.
A wave of head-to-head trials and a biased-agonist newcomer show the GLP-1 class is fragmenting into distinct molecules with measurably different profiles.
A new gene-metabolite map suggests incretin-pathway drugs act on a web of cardiovascular and metabolic systems — not just glucose. Here's what that means for patients in 2026.
New research is beginning to explain why GLP-1 drugs work brilliantly for some and modestly for others — and what comes after the first generation of blockbusters.
A new scoping review reframes obesity as an organelle-level problem — and points to the levers, lifestyle and pharmacological, that actually shift mitochondrial function.
As the GLP-1 class expands beyond weekly injections, three new studies sketch a more complicated risk-benefit map than the headline weight-loss numbers suggest.
A PRISMA-registered meta-analysis pooled 16 studies on adults 55+ and found a link between extra weight and worse oral health — especially gum disease. Here's what that actually means.
Two 2025 preclinical studies hint at where this class is heading — longer-acting molecules, beta-cell-protective stacks, and the first real challengers to semaglutide's throne.