Longevity
Does Infection History Drive Frailty? New Evidence From Baltimore
A long-running cohort study suggests the infections you've weathered may leave a quieter, longer shadow on aging than we assumed.
Longevity
Longevity
Could Ozempic Slow Aging Itself? The First Human Signal Is In
A post-hoc analysis of a randomized trial found semaglutide reduced multiple DNA-methylation aging clocks. It's early, narrow, and genuinely intriguing.
Longevity
What Centenarians' Gut Bugs — and a Nursing Home's — May Be Telling Us About Aging
Two new microbiome studies bracket the human lifespan, hinting that the bacteria in our intestines track with both extreme longevity and cognitive decline. The signals are early, but intriguing.
Longevity
The Cognitive-Reserve Math: How Education and Movement Buy Brain-Healthy Years
A new multistate study of nearly 2,000 older Chileans puts real numbers on the years of cognitive-impairment-free life that schooling and physical activity may add.
Longevity
Personality as a Buffer Against Epigenetic Aging
A new analysis of nearly 3,000 older adults suggests that conscientiousness and openness may help the mind stay sharper than the body's biological clocks would predict — while neuroticism appears to do the opposite.
Longevity
Cognition Plus Muscle: The Double-Hit That Predicts Mortality in Aging
A large Chinese cohort study suggests that losing both thinking power and lean mass together carries a sharper mortality signal than either alone — and points toward a combined training plan.
Longevity
Klotho and Biological Age: A Longevity Biomarker Gets Its Population-Scale Moment
A new analysis of 5,654 American adults links a protein called Klotho to how fast our bodies are actually aging — and it's the kind of signal that nudges Klotho out of the lab and toward your next bloodwork panel.
Longevity
Dementia Before 65: New Cohort Data Shows Early-Onset Risk Looks Different
A harmonised analysis of five major UK and US cohorts finds that the midlife risk factors for early-onset dementia don't always track the familiar late-onset picture — a moderate but consequential signal for how we screen.
Longevity
Sarcopenia Might Be an Inflammation Story — and That Changes Everything
Two new papers reframe age-related muscle loss as a downstream effect of chronic inflammation, immune aging, and a restless gut. Protein shakes alone won't cut it.
Longevity
The Exposome: Why Your ZIP Code May Outweigh Your Supplement Stack
A new review in Atherosclerosis argues that the air you breathe, the noise outside your window, and the climate you live in may shape cardiovascular risk more than the contents of your medicine cabinet.