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A coordinated analysis of four major U.S. cohorts finds that highly specific personality 'nuances' — not just broad traits — track with mortality risk. The strength of the signal is modest, but the pattern is hard to ignore.
Researchers have mapped the first full transcriptome of the olm, an amphibian that lives more than 100 years in the dark. The early findings hint at how some animals stretch a lifespan — and why human biology might one day borrow the trick.
A new three-country study finds that the biological-age tests longevity fans love track smoking, heavy drinking, and BMI with surprising consistency. The catch? They only budge if your behavior does.
Two new commentaries spotlight a single signaling molecule as a clean lever on age-related inflammation. The mouse data are striking. The human verdict is years away.
A new whole-exome analysis of 1,245 long-lived Germans finds rare variants clustering in the mTOR pathway — the same one rapamycin targets — offering rare human evidence for a mechanism mostly studied in animals.
Two 2025 studies converge on measurable biological signatures that set centenarians—and long-lived mammals—apart. The evidence is intriguing, the mechanisms partial, the hype unwarranted.
Transcriptomic clocks are joining PhenoAge and GrimAge in a fast-maturing toolkit — and early longitudinal work hints that ordinary medications may nudge the dial.
A new theoretical model suggests only certain longevity interventions actually shrink the years we spend sick — and the shape of a survival curve might tell us which ones.