Staging the Aging Brain: A New Lifespan Map of Cholinergic Vulnerability
A new review proposes cognitive aging unfolds as a decades-long sequence — and that a midlife branch point may be the window where intervention matters most.
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A new review proposes cognitive aging unfolds as a decades-long sequence — and that a midlife branch point may be the window where intervention matters most.
Early research suggests event-related potentials can flag a quiet form of auditory aging that standard hearing tests miss — and that may matter for focus, conversation, and long-term cognitive health.
A small pilot in healthcare workers finds measurable structural differences in brains clocking 52-plus-hour weeks. The signal is early — but it's the kind endurance athletes, who already think in dose-response curves, should be watching.
A new pathway analysis from the Long Life Family Study untangles how genes, school, and stimulating activities co-act to protect the aging brain — and what that means for the rest of us.
Scientists watching a new fluorescent sensor inside Alzheimer's-model mouse neurons spotted a quieter fuel crisis — and a possible way to refill the tank.
A new Neuron perspective and a longitudinal hippocampal study suggest biological sex shapes how brains age — and that 'one-size-fits-all' cognitive care may be quietly outdated.
A new Nature Aging paper shows that activating a small cluster of neurons can drop mice into a hibernation-like state — and the cooler core temperature, not the fasting, appears to be what bends the epigenetic clock.
A new lifespan MRI study links higher cardiorespiratory fitness to cleaner white matter and fewer brain lesions — a moderate-evidence case that training your engine trains your wiring.