Longevity
What Companion Dogs Are Teaching Us About Human Aging
The Dog Aging Project's Precision Cohort turns 1,000 family pets into a living laboratory for geroscience — and a useful mirror for the rest of us.
healthspan
Longevity
The New Aging Hallmarks: Why Lysosomes, Senescent Cells, and Translation Errors Are the Next Frontier
Three 2025 papers are quietly reshaping the science of why we age — and where the next generation of interventions may aim. Here is what to know, and what to hold loosely.
Longevity
IL-11, the Inflammaging Switch: Can Blocking One Cytokine Extend Healthspan?
Two new commentaries spotlight a single signaling molecule as a clean lever on age-related inflammation. The mouse data are striking. The human verdict is years away.
Longevity
Rewriting the mTOR Aging Playbook: From YTHDF1 to Curcumin
Two new studies sharpen the picture of mTOR as an aging lever — pointing toward more precise ways to dial it down than blunt suppression.
Longevity
Better Biological Clocks: Mortality-Trained Aging Tests Edge Closer to Useful
A new clinical clock called LinAge2 is trained to predict survival, not just guess your age — a quiet but meaningful shift for anyone paying for an epigenetic age test.
Protocols
Healthspan, Not Just Lifespan: A Whole-Life Blueprint for Aging Well
A new European synthesis maps the levers — personal, clinical, and environmental — that may compress the years we spend sick at the end of a longer life.
Longevity
Geroscience Goes Clinical: Targeting Aging Itself to Prevent Disease
A new wave of reviews argues that aging biology — not individual diseases — is medicine's highest-leverage target. Heart failure may be the proving ground.
Longevity
Vitality Capacity: How Lifelong Movement May Reprogram the Aging Body
A new French trial is testing whether decades of exercise preserve a unified signature of biological youth — and population data on diabetes mortality suggests the stakes are higher than we thought.
Longevity
Measuring How Old You Really Are: The Next Generation of Biological-Age Clocks
Transcriptomic clocks are joining PhenoAge and GrimAge in a fast-maturing toolkit — and early longitudinal work hints that ordinary medications may nudge the dial.
Wellness Technology
VR Treadmills and Hospital-Stay Rescue: Engineering Out Age-Related Decline
Two new trials ask whether immersive treadmills and tech-enabled hospital protocols can blunt the quiet erosion of strength, balance and independence in later life. The evidence is early — but the design is sharp.