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New research links a combined insulin-resistance and frailty score to liver disease, ties everyday nutrients to kidney-heart-metabolic mortality, and uses a mouse model to ask why some bodies lose muscle while others don't.
A long-running cohort study suggests the infections you've weathered may leave a quieter, longer shadow on aging than we assumed.
Women rack up more frailty as they age, yet keep outliving the men around them. New centenarian data hints that the answer is hiding in their inflammation.
A 2025 review in Advances in Experimental Medicine and Biology argues frailty — unlike aging itself — is reversible. The two levers: personalized nutrition and structured exercise.
New Berlin Aging Study II data suggest that waking at night to urinate isn't merely a nuisance — it may be an early, observable signal of functional decline in older adults.
Two new studies reframe the conversation around metabolic health in later life — pointing to skeletal muscle, mitochondria, and medication choice as the quiet variables that matter.
A long-running Taiwanese cohort took a closer look at osteosarcopenia — losing bone and muscle at the same time — and the findings are more nuanced than the headlines suggest.
Two new trials ask whether immersive treadmills and tech-enabled hospital protocols can blunt the quiet erosion of strength, balance and independence in later life. The evidence is early — but the design is sharp.
A global expert consensus on exercise for healthy aging arrives alongside trials testing very different anti-frailty levers — from blueberries and protein to a growth-hormone-releasing peptide. Together they reframe frailty as something we can actively push back on.